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The gamma knife directs more than 200 thin beams of gamma radiation at different angles toward a single point in a person's brain. While each beam delivers a trivial amount of radiation, the spot where they converge receives enough energy to destroy that tissue, making the gamma knife a precision tool for attacking small tumors , malformed ...
Leeds Gamma Knife Centre is based in the Institute of Oncology at St James's University Hospital in Leeds, West Yorkshire, England. St. James's Institute of Oncology (Bexley Wing), a National Health Service (NHS) hospital, is the largest cancer research hospital in Europe. [ 1 ]
Radiosurgery is surgery using radiation, [1] that is, the destruction of precisely selected areas of tissue using ionizing radiation rather than excision with a blade. Like other forms of radiation therapy (also called radiotherapy), it is usually used to treat cancer.
Stereotactic surgery is a minimally invasive form of surgical intervention that makes use of a three-dimensional coordinate system to locate small targets inside the body and to perform on them some action such as ablation, biopsy, lesion, injection, stimulation, implantation, radiosurgery (SRS), etc.
The device consists of a small linear accelerator attached to a robotic arm, along with an integrated image guidance system. During treatment, the image guidance system captures 3D images, tracks the movement of tumors, and guides the robotic arm to accurately aim the treatment beam at the moving tumor.
This compelled Leksell to consider other radiation sources and he started designing the cobalt-60 gamma unit, which was fully integrated with the stereotactic system. The development of the ‘‘beam-knife’’ took place after Leksell had been appointed successor to Olivecrona in 1960 and the first unit was inaugurated in 1967.
Cobalt-60, produced by neutron irradiation of ordinary cobalt metal in a reactor, is a high activity gamma-ray emitter, emitting 1.17 and 1.33 MeV gamma rays with an activity of 44 TBq/g (1,200 Ci/g). The main reason for its wide use in radiotherapy is that it has a longer half-life, 5.27 years, than many other gamma emitters. However, this ...
Moreover, OCD has been associated with a malformation of the basal ganglia. [11] The function of this part of the human brain has been mapped to be composed of fiber tracks associated with numerous parallel cortico-striato-thalamocortical circuits (CSTC), which are involved in sensorimotor, motor , oculomotor as well as the cognitive processes ...