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The magic bullet is a scientific concept developed by the German Nobel laureate Paul Ehrlich in 1907. [1] While working at the Institute of Experimental Therapy (Institut für experimentelle Therapie), Ehrlich formed an idea that it could be possible to kill specific microbes (such as bacteria), which cause diseases in the body, without harming the body itself.
In 1909, Sahachiro Hata went to work in Paul Ehrlich's laboratory, the National Institute for Experimental Therapeutics, in Frankfurt, Germany to help Ehrlich in his quest to develop a treatment for syphilis called the 'magic bullet.' [4] The causative agent of syphilis was discovered to be the spirochete Treponema pallidum by Fritz Schaudinn ...
Ehrlich's life and work was featured in the 1940 U.S. film Dr. Ehrlich's Magic Bullet with Edward G. Robinson in the title role. It focused on Salvarsan (arsphenamine, "compound 606"), his cure for syphilis. Since the Nazi government was opposed to this tribute to a Jewish scientist, attempts were made to keep the film a secret in Germany.
Dr. Ehrlich's Magic Bullet is a 1940 American biographical film starring Edward G. Robinson and directed by William Dieterle, based on the true story of the German doctor and scientist Dr. Paul Ehrlich. The film was released by Warner Bros., with some controversy over raising the subject of syphilis in a major studio release.
The decline was driven by a 13% drop in such syphilis diagnoses among gay and bisexual men, who are about 2% of the adult population but have historically accounted for nearly half of such cases.
Rabbits had been used to test treatments for syphilis since the early twentieth century, when Sahachiro Hata injected them with arsphenamine, which became known as "the magic bullet" for treating syphilis. They were later injected in the 1940s with penicillin as part of research into methods for preventing syphilis.
Arsphenamine was used to treat the disease syphilis because it is toxic to the bacterium Treponema pallidum, a spirochete that causes syphilis. [ 6 ] Arsphenamine was originally called "606" because it was the sixth in the sixth group of compounds synthesized for testing; it was marketed by Hoechst AG under the trade name "Salvarsan" in 1910.
Dr. Ehrlich's Magic Bullet, a 1940 Hollywood biopic about syphilis researcher Paul Ehrlich, starring Edward G. Robinson "Magic Bullet Theory", the name commonly assigned to the single-bullet theory by its critics in the investigation of the John F. Kennedy assassination