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Tobacco water, tobacco juice, tobacco dust juice, or tobacco lime is a traditional organic insecticide used in domestic gardening. [ 1 ] [ 2 ] In The English Physician Enlarged of 1681, Nicholas Culpeper recommended tobacco juice to kill lice on children's heads, referencing it as an insecticide poison.
Kidney toxicity [5] associated with kidney failure; associated with development of cancer, particularly of the urinary tract, known carcinogen [8] [9] Atractylate Atractylis gummifera: Liver damage, [3] nausea, vomiting, epigastric and abdominal pain, diarrhoea, anxiety, headache and convulsions, often followed by coma [10]
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All parts of the plant are highly toxic to humans and most animals. The bright red berries contain calcium oxalate raphides and soluble oxalates of saponins (as well as trace amounts of cyanogens and coniine) which can cause skin, mouth, and throat irritation, resulting in swelling, burning pain, breathing difficulties, and stomach upset.
The toxicity of oxalic acid is due to kidney failure caused by precipitation of solid calcium oxalate. [67] Oxalate is known to cause mitochondrial dysfunction. [68] Ingestion of ethylene glycol results in oxalic acid as a metabolite which can also cause acute kidney failure.
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
It differs from moist snuff or chewing tobacco in that it is made from steam-cured tobacco leaves, rather than fire-cured ones, and its health effects are markedly different, with epidemiological studies showing lower rates of cancer and other tobacco-related health problems than cigarettes, American "chewing tobacco", Indian gutka or African ...
Between 1% and 15% of people globally are affected by kidney stones at some point. [14] [15] In 2015, they caused about 16,000 deaths worldwide. [16] Some of the oxalate in urine is produced by the body. Calcium and oxalate in the diet play a part but are not the only factors that affect the formation of calcium oxalate stones.