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Cellulose nanocrystals (CNCs), or nanocrystalline cellulose (NCC), are highly crystalline, rod-like nanoparticles. [6] [7] They are usually covered by negatively charged groups that render them colloidally stable in water. They are typically shorter than CNFs, with a typical length of 100 to 1000 nanometers. [8]
The use of monoclonal antibodies for therapy is now widespread for treatment of cancers and inflammatory diseases. Using cellulose sulphate technology, scientists have successfully encapsulated antibody producing hybridoma cells and demonstrated subsequent release of the therapeutic antibody from the capsules.
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
As the development of nanomedicine continues to develop and becomes a potential treatments for diseases, regulatory challenges have come to light. This section will highlight some of the regulatory considerations and challenges faced by the Food and Drug Administration (FDA), the European Medicine Agency (EMA), and each manufacturing organization.
It is a technique for which research is ongoing, but has been used for a number of skin problems including scarring and acne. [1] Some studies have also shown that when combined with minoxidil treatment, microneedling is able to treat hair loss more effectively than minoxidil treatment alone.
Aside from "topical" products (creams, ointments) and injectables (collagenase), treatments for cellulite include non-invasive therapy such as mechanical suction or mechanical massage. Energy-based devices include radio frequency with deep penetration of the skin, ultrasound, [ 11 ] cryotherapy chambers, [ 12 ] laser and pulsed-light devices.
Nanodiamonds are well-absorbed by human skin. They also absorb more of the ingredients in skin care products than skin itself. Thus they cause more of the ingredients to penetrate the deeper layers of the skin. Nanodiamonds also form strong bonds with water, helping to hydrate the skin. [3]
CNTs have several unique chemical, size, optical, electrical and structural properties that make them attractive as drug delivery and biosensing platforms for the treatment of various diseases [5] and the noninvasive monitoring of blood levels and other chemical properties of the human body, respectively. [4]