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  2. 1775–1782 North American smallpox epidemic - Wikipedia

    en.wikipedia.org/wiki/1775–1782_North_American...

    The most common type of smallpox, ordinary, historically has devastated populations with a 30% death rate. The smallpox virus is transmittable through bodily fluids and materials contaminated with infected materials. Generally, face-to-face contact is required for an individual to contract smallpox as a result of an interaction with another human.

  3. History of smallpox - Wikipedia

    en.wikipedia.org/wiki/History_of_smallpox

    The clearest description of smallpox from pre-modern times was given in the 9th century by the Persian physician, Muhammad ibn Zakariya ar-Razi, known in the West as "Rhazes", who was the first to differentiate smallpox from measles and chickenpox in his Kitab fi al-jadari wa-al-hasbah (The Book of Smallpox and Measles). [27]

  4. 1738–1739 North Carolina smallpox epidemic - Wikipedia

    en.wikipedia.org/wiki/1738–1739_North_Carolina...

    The epidemic was probably spread to the Cherokee by white traders in the summer of 1739. The virus may also have come from Spanish Florida. 900 Cherokees had joined the British to fight the Spanish in Florida in 1739, and may have brought smallpox back with them. Cherokee "religious physicians" blamed the plague on "adulterous intercourse ...

  5. Native American disease and epidemics - Wikipedia

    en.wikipedia.org/wiki/Native_American_disease...

    During the 1770s, smallpox killed at least 30% (tens of thousands) of the Northwestern Native Americans. [74] [75] The smallpox epidemic of 1780–1782 brought devastation and drastic depopulation among the Plains Indians. [76] By 1832, the federal government of the United States established a smallpox vaccination program for Native Americans. [77]

  6. 1770s Pacific Northwest smallpox epidemic - Wikipedia

    en.wikipedia.org/wiki/1770s_Pacific_Northwest...

    The 1520s smallpox epidemic spread from Mesoamerica into adjacent maize-growing regions in North America.A population decline in the Columbia Basin, evidenced archaeologically by a sharp regional decline in artifacts and structures in the early 1500s, has been tentatively linked to a spread of this outbreak, but greatly predates any written record in the region.

  7. 1721 Boston smallpox outbreak - Wikipedia

    en.wikipedia.org/wiki/1721_Boston_smallpox_outbreak

    On 22 February 1722, it was officially announced that no new cases of smallpox were appearing in Boston and the disease was in decline. [1] In the outbreak's aftermath, with over 800 Bostonians dead and many more disfigured from smallpox, Boylston's 247 inoculated patients had a 2% death rate versus the 15% [ 8 ] [ 5 ] of people who died if ...

  8. Onesimus (Bostonian) - Wikipedia

    en.wikipedia.org/wiki/Onesimus_(Bostonian)

    Onesimus (late 1600s–1700s [1]) was an African (likely Akan) man who was instrumental in the mitigation of smallpox in Boston, Massachusetts.. He introduced his enslaver, Puritan clergyman Cotton Mather, to the principle and procedure of the variolation method of inoculation, which prevented smallpox and laid the foundation for the development of vaccines.

  9. Influx of disease in the Caribbean - Wikipedia

    en.wikipedia.org/wiki/Influx_of_disease_in_the...

    Smallpox is among the most notable of diseases in the Columbian Exchange due to the high number of deaths and impact on life for Indigenous societies. [1] [5] Smallpox first broke out in the Americas on the island of Hispaniola in 1518. [7] The disease was carried over from Europe, where it had been endemic for over seven hundred years. [5]