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Mirabegron, sold under the brand name Myrbetriq among others, is a medication used to treat overactive bladder. [5] Its benefits are similar to antimuscarinic medication such as solifenacin or tolterodine. [6] It is taken by mouth. [5] Common side effects include high blood pressure, headaches, and urinary tract infections. [5]
More recently pharmaceutical companies have developed selective β 3-AR agonists targeted at urinary inconsistencies and in 2012 Mirabegron (trade name Myrbetriq and Betmiga) was the first β 3-AR agonist to be approved in the United States and Europe for the treatment of overactive bladder (OAB) syndrome. [1] [2]
Here vibegron differs from the previous overactive bladder drug mirabegron, which was known to be associated in various drug–drug interactions by inhibiting CYP2D6 or inducing CYP3A4, CYP2D6 and CYP2C9 in the liver. [13] [4] [14] [15] [16] [17]
What is overactive bladder? Overactive bladder isn’t a disease but rather a syndrome defined by a collection of symptoms, says Jennifer Linehan, MD, a urologist and associate professor of ...
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Overactive bladder (OAB) is a common condition where there is a frequent feeling of needing to urinate to a degree that it negatively affects a person's life. [2] The frequent need to urinate may occur during the day, at night , or both. [ 4 ]
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