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Collagen alpha-1(VII) chain is a protein that in humans is encoded by the COL7A1 gene. [5] It is composed of a triple helical, collagenous domain flanked by two non-collagenous domains, and functions as an anchoring fibril between the dermal-epidermal junction in the basement membrane. [ 6 ]
As of 2009, a 50-residue protein could be simulated atom-by-atom on a supercomputer for 1 millisecond. [36] As of 2012, comparable stable-state sampling could be done on a standard desktop with a new graphics card and more sophisticated algorithms. [37] A much larger simulation timescales can be achieved using coarse-grained modeling. [38] [39]
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
Collagen alpha-1(VIII) chain is a protein that in humans is encoded by the COL8A1 gene. [5] [6] This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a ...
Collagen is used as a natural wound dressing because it has properties that artificial wound dressings do not have. It resists bacteria, which is vitally important in wound dressing. As a burn dressing, collagen helps it heal fast by helping granulation tissue to grow over the burn.
1277 12842 Ensembl ENSG00000108821 ENSMUSG00000001506 UniProt P02452 P11087 RefSeq (mRNA) NM_000088 NM_007742 RefSeq (protein) NP_000079 NP_031768 Location (UCSC) Chr 17: 50.18 – 50.2 Mb Chr 11: 94.83 – 94.84 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Collagen, type I, alpha 1, also known as alpha-1 type I collagen, is a protein that in humans is encoded by the COL1A1 gene ...
107581 Ensembl ENSG00000084636 ENSMUSG00000040690 UniProt Q07092 Q8BLX7 RefSeq (mRNA) NM_001856 NM_028266 RefSeq (protein) NP_001847 NP_082542 NP_001391281 NP_001391282 Location (UCSC) Chr 1: 31.65 – 31.7 Mb Chr 4: 129.94 – 129.99 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Collagen alpha-1(XVI) chain is a protein that in humans is encoded by the COL16A1 gene. Function This ...
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type.