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On December 20, 2021, the FDA approved Cabotegravir (Apretude), which was the first injectable drug for PrEP that is taken every two months. [5] There has been some evidence that other regimens, like ones based on the antiretroviral agent Maraviroc, could potentially prevent HIV infection. [102]
Emtricitabine/tenofovir is generally well tolerated. Some of its side effects include: [7] Rare: lactic acidosis, liver dysfunction, worsening of hepatitis B infection; Common: headache, abdominal pain, decreased weight, nausea, diarrhea, and decreased bone density
By comparison, nearly four years passed after Truvada’s approval as PrEP before a breakthrough infection was first documented in someone faithfully taking that drug. To date, there have been a ...
(Reuters) -Gilead Sciences said on Thursday a late-stage study showed its long-acting injectable drug was more effective in preventing HIV infection in women compared to its existing daily pill ...
Gilead also manufactures Truvada and Descovy, the two daily oral tablets approved for use as pre-exposure prophylaxis, or PrEP. ... The pharma giant has already secured approval for the injectable ...
The drug works by inhibiting reverse transcriptase, the enzyme that copies HIV RNA into new viral DNA. By interfering with this process, which is central to the replication of HIV, emtricitabine can help to lower the amount of HIV, or " viral load ", in a patient's body and can indirectly increase the number of immune system cells (namely T ...
It can be used by mouth or by slow injection into a vein. [6] Common side effects include headaches, fever, and nausea. [6] Serious side effects include liver problems, muscle damage, and high blood lactate levels. [6] It is commonly used in pregnancy and appears to be safe for the fetus. [6]
Common side effects include nausea, rash, diarrhea, headache, pain, depression, and weakness. [4] Severe side effects include high blood lactate and an enlarged liver. [4] There are no absolute contraindications. [4] It is often recommended during pregnancy and appears to be safe. [4]
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