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Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer , while one in the first part of the intestines is a duodenal ulcer . [ 1 ]
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Antibiotics and agents to reduce gastric acid secretion are used in combinations to treat Helicobacter pylori (H. pylori)-induced peptic ulcer disease (PUD), an ulceration in the gastric region. Antibiotics include amoxicillin, clarithromycin and metronidazole.
Even though milk and other dairy products are permissible in a bland diet, consumption may interfere with the homeostatic processes involved in digestion; prominently for peptic ulcer patients. In an early study, milk was found to have a short-lived gastric acid neutralising effect; which may lead to milk-alkali syndrome and eventually ...
He was most notable for his pioneering treatment for peptic ulcer disease; linking the acidity of the stomach to the severity of the ulcers, he prescribed hourly servings of milk and cream supplemented by other forms of antacids. This treatment revolutionized the healing of the ulcers, but was ultimately superseded due to its inability to ...
Helicobacter pylori eradication protocols is a standard name for all treatment protocols for peptic ulcers and gastritis in the presence of Helicobacter pylori infection. The primary goal of the treatment is not only temporary relief of symptoms but also total elimination of H. pylori infection.
This is a timeline of the events relating to the discovery that peptic ulcer disease and some cancers are caused by H. pylori. In 2005, Barry Marshall and Robin Warren were awarded the Nobel Prize in Physiology or Medicine for their discovery that peptic ulcer disease (PUD) was primarily caused by Helicobacter pylori , a bacterium with affinity ...
Mucosal disruption in acid peptic disease patients can be caused by infection, barrier disruption, or gastric acid hypersecretion.Acid peptic diseases can arise due to various risk factors such as Helicobacter pylori infection, alcoholism, tobacco use, cocaine and amphetamine use, nonsteroidal anti-inflammatory drug use (NSAIDs), fasting, Zollinger-Ellison syndrome, angiogenesis inhibitor ...