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Meprobamate—marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others—is a carbamate derivative used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benzodiazepines due to their wider therapeutic index (lower risk of toxicity at therapeutically prescribed doses) and lower incidence of serious side effects.
Cyclopentamine is the cyclopentane homolog of propylhexedrine, differing only in terms of the contracted ring size of a cyclopentane, containing one —CH 2 — unit less than the cyclohexyl group. In terms of the acyclic part of the molecule, both cyclopentamine and propylhexedrine are the same as methamphetamine , all three molecules ...
1-(3,4-Methylenedioxyphenyl)-2-propylaminopentane (MPAP), also known as 3,4-methylenedioxy-α,N-dipropylphenethylamine, N-propyl-1,3-benzodioxolylpentanamine (PDBP), or propyl-K, is a monoaminergic activity enhancer (MAE) of the phenethylamine, amphetamine, and α-propylphenethylamine families that is closely related to phenylpropylaminopentane (PPAP). [1]
Examples include 2-pentyl- and 2-heptylcyclopentanone. [4] It is a versatile synthetic intermediate, being a precursor to cyclopentobarbital. [5] Cyclopentobarbital, a drug made from cyclopentanone. Cyclopentanone is also used to make cyclopentamine, the pesticide pencycuron, and pentethylcyclanone. [5]
2-Methyl-6-(phenylethynyl)pyridine (MPEP) is a research drug which was one of the first compounds found to act as a selective antagonist for the metabotropic glutamate receptor subtype mGluR5. After being originally patented as a liquid crystal for LCDs, it was developed by the pharmaceutical company Novartis in the late 1990s. [ 1 ]
2-Pentanone or methyl propyl ketone (MPK) is a ketone and solvent of minor importance. It is comparable to methyl ethyl ketone , but has a lower solvency and is more expensive. [ 5 ] It occurs naturally in Nicotiana tabacum (Tobacco) [ 6 ] and blue cheese as a metabolic product of Penicillium mold growth.
Cypenamine is a homolog of tranylcypromine, containing an expanded alicyclic ring that is two methylene units larger than the highly strained/reactive cyclopropane. The cyclohexane homologue has been reported, although the LD 50 s were all less than for plain amphetamine, it was still a functional stimulant.
Doses up to 200 mg/kg are not observed to have stimulant properties, and a dosage of 20 mg/kg does not potentiate the effects of dextroamphetamine in rats. [1] It displays possible cholinergic properties, and potentiates dopamine while partially inhibiting serotonin. [1] PRL-8-53 reverses the catatonic and ptotic effects of reserpine. [1] [3]