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However, celery has a thermic effect of around 8%, much less than the 100% or more required for a food to have "negative calories". [5] Diets based on negative-calorie food do not work as advertised but can lead to weight loss because they satisfy hunger by filling the stomach with food that is not calorically dense. [4]
Phentermine is used for a short period of time to promote weight loss, if exercise and calorie reduction are not sufficient, and in addition to exercise and calorie reduction. [5] [15] Phentermine is approved for up to 12 weeks of use and most weight loss occurs in the first weeks. [15]
[10] [18] When used in routine care, there is evidence that VLCDs achieve average weight loss at 1 year around 10 kilograms (22 lb) [19] or about 4% more weight loss over the short term. [20] VLCDs can achieve higher short-term weight loss compared to other more modest or gradual calorie restricted diets, and the maintained long-term weight ...
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