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Pemetrexed is also recommended in combination with carboplatin and pembrolizumab for the first-line treatment of advanced non-small cell lung cancer. [12] [13] However, the relative efficacy or toxicity of pemetrexed-cisplatin versus pemetrexed-carboplatin has not been established beyond what is generally thought about cisplatin or carboplatin doublet drug therapy.
Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim only to prolong life or to reduce symptoms (palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called medical oncology. [1] [2]
Chemotherapy for cancer applies is an example. The standard of care (sometimes also called the "gold standard") for the adjuvant treatment of stage III colon cancer is the FOLFOX chemotherapy protocol (used in Europe, Japan, Canada, and Australia) and respectively the FLOX chemotherapy protocol (used in the USA).
Lewis Carroll's doublet in Vanity Fair, March 1897 changing the word "head" to "tail" in five steps, one letter at a time. Word ladder (also known as Doublets, [1] word-links, change-the-word puzzles, paragrams, laddergrams, [2] or word golf) is a word game invented by Lewis Carroll. A word ladder puzzle begins with two words, and to solve the ...
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...
Chemo-protective agents have only recently been introduced as a factor involved with chemotherapy with the intent to assist those cancer patients that require treatment, which as an result, improves the patients' quality of life. Amifostine; A common chemo-protective agent that has been approved by the FDA. Examples [2] include:
Targeted therapy of lung cancer refers to using agents specifically designed to selectively target molecular pathways responsible for, or that substantially drive, the malignant phenotype of lung cancer cells, and as a consequence of this (relative) selectivity, cause fewer toxic effects on normal cells.
Doublet (potential flow), fluid flow due to a source–sink combination; Doublet, or dimeresia howellii, a tiny flowering plant; Doublet earthquake, two earthquakes associated by space and time; Doublet state, a state in quantum physics of a system with a spin of 1 ⁄ 2; Unit doublet, in mathematics, the derivative of the Dirac delta function