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Hydrocodone: Respiratory depression, extreme somnolence progressing towards coma, muscle limpness, cold and clammy skin, slow heart rate, low blood pressure, abrupt loss of heart function, and death may occur.
Hydrocodone is a highly selective full agonist of the μ-opioid receptor (MOR). [28] [54] [49] This is the main biological target of the endogenous opioid neuropeptide β-endorphin. [55] Hydrocodone has low affinity for the δ-opioid receptor (DOR) and the κ-opioid receptor (KOR), where it is an agonist similarly. [49]
Depending on the specific formulation of Vicodin, it can contain 300 mg to 750 mg of acetaminophen and 2.5 mg to 10 mg of hydrocodone. Vicodin's acetaminophen content has led to criticism that the ...
The maximum daily limit of acetaminophen is 4 grams per day for someone with a healthy liver. It is also highly recommended to not go over the maximum daily limit. Exceeding the maximum daily limit could involve severe liver toxicity , liver failure, kidney failure , or even death. [ 4 ]
An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and ...
Follow @leokornsun The Food and Drug Administration recently issued a warning regarding higher doses of acetaminophen, the active ingredient in over-the-counter painkillers such as Johnson ...
Signs and symptoms of opioid overdose include, but are not limited to: [39] Pin-point pupils may occur. Patient presenting with dilated pupils may still be experiencing an opioid overdose. Decreased heart rate; Decreased body temperature; Decreased breathing; Altered level of consciousness. People may be unresponsive or unconscious.
These include morphine, codeine, oxycodone and hydrocodone, with brand names OxyContin, Vicodin and Lortab. Depressants that are used to treat anxiety and sleep disorders include brands like ...