Search results
Results from the WOW.Com Content Network
In conventional chemotherapy, a dose close to the maximum tolerated dose is administered in a bolus manner to achieve cytotoxic effects on tumor cells. [5] However, the side effects are often significant as the cytotoxic agents also kill the fast-dividing cells normally present in the body, such as bone marrow cells and epithelial cells of the gastrointestinal tract. [6]
Carboplatin, a cisplatin analogue, was developed by Bristol Myers Squibb and the Institute of Cancer Research in order to reduce the toxicity of cisplatin. [6] [20] It gained U.S. Food and Drug Administration (FDA) approval for carboplatin, under the brand name Paraplatin, in March 1989. Starting in October 2004, generic versions of the drug ...
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations.In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy.
For the last couple of months, they’ve been rationing by rounding down doses of carboplatin by 10%, which Gordan said doesn’t diminish the drug’s efficacy. “We have been rounding down for ...
Oncologists are already individualizing dosing of some cancer drugs based on exposure. Carboplatin [29]: 4 and busulfan [30] [31] dosing rely upon results from blood tests to calculate the optimal dose for each person. Simple blood tests are also available for dose optimization of methotrexate, [32] 5-FU, paclitaxel, and docetaxel. [33] [34]
Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]
Wegovy, a higher-dose version of semaglutide, was approved in 2021 for weight loss in people with obesity or overweight with obesity-related conditions like high blood pressure (hypertension) and ...
Group meditation and sound baths: reduce stress . Mindfulness can feel daunting, but it's necessary for your mental well-being. "Chronic stress can take a toll on our mental health," says Kress ...