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Midodrine is a prodrug which forms the active metabolite, desglymidodrine, which is an α 1-adrenergic receptor agonist and exerts its actions via activation of α 1-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.
Fullerenes had been predicted for some time, but only after their accidental synthesis in 1985 were they detected in nature [3] [4] and outer space. [5] [6] The discovery of fullerenes greatly expanded the number of known allotropes of carbon, which had previously been limited to graphite, diamond, and amorphous carbon such as soot and charcoal.
A review of works on fullerene toxicity by Lalwani et al. found little evidence that C 60 is toxic. [1] The toxicity of these carbon nanoparticles varies with dose, duration, type (e.g., C 60, C 70, M@C 60, M@C 82), functional groups used to water-solubilize these nanoparticles (e.g., OH, COOH), and method of administration (e.g., intravenous, intraperitoneal).
Spherical fullerenes are also called buckyballs, and they resemble the balls used in football (soccer). Fullerenes are similar in structure to graphite, which is composed of stacked graphene sheets of linked hexagonal rings; but they may also contain pentagonal (or sometimes heptagonal) rings.
Fullerene chemistry is a field of organic chemistry devoted to the chemical properties of fullerenes. [1] [2] [3] Research in this field is driven by the need to functionalize fullerenes and tune their properties. For example, fullerene is notoriously insoluble and adding a suitable group can enhance solubility. [1]
Polyfullerene is a basic polymer of the C 60 monomer group, in which fullerene segments are connected via covalent bonds into a polymeric chain without side or bridging groups. They are called intrinsic polymeric fullerenes, or more often all C 60 polymers. Fullerene can be part of a polymer chain in many different ways.
There are many forms in which herbs can be administered, the most common of which is a liquid consumed as a herbal tea or a (possibly diluted) plant extract. [ 25 ] Herbal teas , or tisanes, are the resultant liquid of extracting herbs into water, though they are made in a few different ways.
Cat's claw is linked to some serious side effects, although the extent of those effects is not known". [106] Venus flytrap – its extract is promoted as a cure for skin cancer. Venus flytrap – a carnivorous plant, the extract of which has been promoted as a treatment for a variety of human ailments including skin cancer. According to the ...