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  2. Thiamine deficiency - Wikipedia

    en.wikipedia.org/wiki/Thiamine_deficiency

    Thiamine deficiency is a medical condition of low levels of thiamine (vitamin B 1). [1] A severe and chronic form is known as beriberi. [1] [7] The name beriberi was possibly borrowed in the 18th century from the Sinhalese phrase බැරි බැරි (bæri bæri, “I cannot, I cannot”), owing to the weakness caused by the condition.

  3. Wernicke encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Wernicke_encephalopathy

    Thiamine deficiency and errors of thiamine metabolism are believed to be the primary cause of Wernicke encephalopathy. Thiamine, also called B 1, helps to break down glucose. Specifically, it acts as an essential coenzyme to the TCA cycle and the pentose phosphate shunt. Thiamine is first metabolised to its more active form, thiamine ...

  4. Korsakoff syndrome - Wikipedia

    en.wikipedia.org/wiki/Korsakoff_syndrome

    Korsakoff syndrome (KS) [1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation.This neurological disorder is caused by a deficiency of thiamine (vitamin B 1) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol. [2]

  5. Wernicke–Korsakoff syndrome - Wikipedia

    en.wikipedia.org/wiki/Wernicke–Korsakoff_syndrome

    Frequently, secondary to thiamine deficiency and subsequent cytotoxic edema in Wernicke encephalopathy, patients will have marked degeneration of the mammillary bodies. Thiamine (vitamin B 1) is an essential coenzyme in carbohydrate metabolism and is also a regulator of osmotic gradient. Its deficiency may cause swelling of the intracellular ...

  6. Leigh syndrome - Wikipedia

    en.wikipedia.org/wiki/Leigh_syndrome

    In children with Leigh-syndrome associated ventricular septal defects, caused by pyruvate dehydrogenase deficiency, high forehead and large ears are seen; facial abnormalities are not typical of Leigh syndrome. [7] However, respiratory failure is the most common cause of death in people with Leigh syndrome.

  7. Alcoholic cardiomyopathy - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_cardiomyopathy

    The diagnosis of alcoholic cardiomyopathy is typically made based on a combination of the patient's medical history, physical examination, and diagnostic tests. [8] Firstly, the doctor will ask the patient about their alcohol consumption habits, as well as any symptoms they may have experienced, such as shortness of breath or swelling in the ...

  8. Dying To Be Free - The Huffington Post

    projects.huffingtonpost.com/dying-to-be-free...

    Still, he relapsed five days after graduating from the clinic. It would take him another year and a half, along with a platoon of understanding adults, before he found sobriety through another 12-step program. Now, as a physician, he knew he had to track down the clinic’s dropouts and their families, and ask them what Hazelden was doing wrong.

  9. Cerebellar degeneration - Wikipedia

    en.wikipedia.org/wiki/Cerebellar_degeneration

    A diagnosis for cerebellar degeneration is regarded after any of the aforementioned signs and symptoms surface. For genetically classified forms of cerebellar degeneration, genetic testing can be carried out in order to confirm or deny the diagnosis, where this form of testing is only possible if the gene responsible for the cause of the ...