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Tizanidine was approved for medical use in the United States in 1996. [5] It is available as a generic medication. [3] In 2022, it was the 94th most commonly prescribed medication in the United States, with more than 6 million prescriptions. [7] [8]
Muscle relaxants such as tizanidine are prescribed in the treatment of tension headaches. [20] Diazepam and carisoprodol are not recommended for older adults, pregnant women, or people who have depression or for those with a history of drug or alcohol addiction. [21]
Shingles, also known as herpes zoster or zona, [6] is a viral disease characterized by a painful skin rash with blisters in a localized area. [2] [7] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [1]
Duloxetine is one of the most commonly used prescription medications in the U.S. Patients with depression are usually prescribed 40 to 60 milligrams per day, with a potential increase of up to 120 ...
Governmental controls on manufacture, supply, and prescription attempt to reduce problematic medical drug use; worldwide efforts to combat trafficking in psychoactive drugs are commonly termed the "war on drugs". Ethical concerns have also been raised about the overuse of these drugs clinically and about their marketing by manufacturers. [9]
The risk factors [110] for treatment resistant depression are: the duration of the episode of depression, severity of the episode, if bipolar, lack of improvement in symptoms within the first couple of treatment weeks, anxious or avoidant and borderline comorbidity and old age. Treatment resistant depression is best handled with a combination ...
Although the exact origin of depression is unclear, it is believed to involve biological, psychological, and social aspects. [2] Socioeconomic status, life experience, genetics, and personality traits are believed to be factors in the development of depression and may represent an increased risk of developing a major depressive episode. [3]
[22] [23] Liothyronine (synthetic T 3) is a type of thyroid hormone and has been associated with improvement in mood and depression symptoms. Benzodiazepines may improve treatment-resistant depression by decreasing the adverse side effects caused by some antidepressants and therefore increasing patient compliance. [24]
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