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A motor neuron (or motoneuron or efferent neuron [1]) is a neuron whose cell body is located in the motor cortex, brainstem or the spinal cord, and whose axon (fiber) projects to the spinal cord or outside of the spinal cord to directly or indirectly control effector organs, mainly muscles and glands. [2]
Betz cells are upper motor neurons that send their axons down to the spinal cord via the corticospinal tract, where in humans they synapse directly with anterior horn cells, which in turn synapse directly with their target muscles.
In that view, a neuron in the motor cortex sends an axon or projection to the spinal cord and forms a synapse on a motor neuron. The motor neuron sends an electrical impulse to a muscle. When the neuron in the cortex becomes active, it causes a muscle contraction. The greater the activity in the motor cortex, the stronger the muscle force.
The activating function represents the rate of membrane potential change if the neuron is in resting state before the stimulation. Its physical dimensions are V/s or mV/ms. In other words, it represents the slope of the membrane voltage at the beginning of the stimulation. [8]
This feedback allows for more fine control of movement. In the brain, proprioceptive integration occurs in the somatosensory cortex, and motor commands are generated in the motor cortex. In the spinal cord, sensory and motor signals are integrated and modulated by motor neuron pools called central pattern generators (CPGs).
A neuroeffector junction is a site where a motor neuron releases a neurotransmitter to affect a target—non-neuronal—cell. This junction functions like a synapse.However, unlike most neurons, somatic efferent motor neurons innervate skeletal muscle, and are always excitatory.
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The B31/B32 autapse was unable to play a role in initiating the neuron's activity, although it is believed to have helped sustain the neuron's depolarized state. The extent to which autapses maintain depolarization remains unclear, particularly since other components of the neural circuit (i.e. B63 neurons) are also capable of providing strong ...