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  2. Prognosis - Wikipedia

    en.wikipedia.org/wiki/Prognosis

    Prognosis (Greek: πρόγνωσις "fore-knowing, foreseeing"; pl.: prognoses) is a medical term for predicting the likelihood or expected development of a disease, including whether the signs and symptoms will improve or worsen (and how quickly) or remain stable over time; expectations of quality of life, such as the ability to carry out daily activities; the potential for complications and ...

  3. Lead time bias - Wikipedia

    en.wikipedia.org/wiki/Lead_time_bias

    Another example is when early diagnosis by screening may not prolong the life of someone but just determine the propensity of the person to a disease or medical condition, such as by DNA testing. [1] No additional life span has been gained, and the patient may even be subject to added anxiety as the patient must live for longer with knowledge ...

  4. Case fatality rate - Wikipedia

    en.wikipedia.org/wiki/Case_fatality_rate

    The mortality rate – often confused with the CFR – is a measure of the relative number of deaths (either in general, or due to a specific cause) within the entire population per unit of time. [2] A CFR, in contrast, is the number of deaths among the number of diagnosed cases only, regardless of time or total population.

  5. Clinical significance - Wikipedia

    en.wikipedia.org/wiki/Clinical_significance

    In broad usage, the "practical clinical significance" answers the question, how effective is the intervention or treatment, or how much change does the treatment cause. In terms of testing clinical treatments, practical significance optimally yields quantified information about the importance of a finding, using metrics such as effect size, number needed to treat (NNT), and preventive fraction ...

  6. Nocebo - Wikipedia

    en.wikipedia.org/wiki/Nocebo

    A nocebo effect is said to occur when a patient's expectations for a treatment cause the treatment to have a worse effect than it otherwise would have. [ 1 ] [ 2 ] For example, when a patient anticipates a side effect of a medication, they can experience that effect even if the "medication" is actually an inert substance. [ 1 ]

  7. Causal analysis - Wikipedia

    en.wikipedia.org/wiki/Causal_analysis

    Causal analysis is the field of experimental design and statistics pertaining to establishing cause and effect. [1] Typically it involves establishing four elements: correlation, sequence in time (that is, causes must occur before their proposed effect), a plausible physical or information-theoretical mechanism for an observed effect to follow from a possible cause, and eliminating the ...

  8. Signs and symptoms - Wikipedia

    en.wikipedia.org/wiki/Signs_and_symptoms

    Inflammation for example has a recognised group of cardinal signs and symptoms, [44] as does exacerbations of chronic bronchitis, [45] and Parkinson's disease. In contrast to a pathognomonic cardinal sign, the absence of a sign or symptom can often rule out a condition. This is known by the Latin term sine qua non.

  9. Causal inference - Wikipedia

    en.wikipedia.org/wiki/Causal_inference

    Causal inference is the process of determining the independent, actual effect of a particular phenomenon that is a component of a larger system. The main difference between causal inference and inference of association is that causal inference analyzes the response of an effect variable when a cause of the effect variable is changed.