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As a result, kidney function and blood levels of lithium are monitored in patients being treated with lithium. [2] Therapeutic plasma levels of lithium range from 0.5 to 1.5 mEq/L, with levels of 0.8 or higher being desirable in acute mania. [14] Lithium levels should be above 0.6 mEq/L to reduce both manic and depressive episodes in patients. [15]
Lithium – Lithium is the "classic" mood stabilizer, the first to be approved by the US FDA, and still popular in treatment. Therapeutic drug monitoring is required to ensure lithium levels remain in the therapeutic range: 0.6 to 0.8 or 0.8–1.2 mEq/L (or millimolar). Signs and symptoms of toxicity include nausea, vomiting, diarrhea, and ...
Lithium carbonate can induce a 1–2 kg of weight gain. [70] In addition to tremors, lithium treatment appears to be a risk factor for development of parkinsonism-like symptoms, although the causal mechanism remains unknown. [71] Most side effects of lithium are dose-dependent. The lowest effective dose is used to limit the risk of side effects.
Symptoms of Bipolar Disorder The single most telling symptom of bipolar disorder is the episodic oscillation between high and low mood states — characteristic shifts between depression, normal ...
Lithium prevents mood relapse and works especially well in BP-II patients who experience rapid-cycling. [53] Almost all BP-II patients who take lithium have a decrease in the amount of time they spend ill and a decrease in mood episodes. [53] Along with medication, other forms of therapy have been shown to be beneficial for BP-II patients.
Lithium citrate was removed from 7Up in 1948 [5] after the Food and Drug Administration banned its use in soda. [6] Lithium citrate is used as a mood stabilizer and is used to treat mania, hypomania, depression and bipolar disorder. [7] It can be administered orally in the form of a syrup. [7]
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