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They are the causative agents of blastomycosis, a systemic mycosis in immunocompromised patients. [ 1 ] [ 2 ] Blastomyces Gilchrist & W.R. Stokes (1898) was an illegitimate homonym of Blastomyces Costantin & Rolland (1888) (a synonym of Chrysosporium ), but has now been conserved against the earlier name because of its widespread use in ...
Blastomycosis is endemic to the eastern United States and Canada, especially the Ohio and Mississippi River valleys, the Great Lakes, and the St. Lawrence River valley. [6] In these areas, there are about 1 to 2 cases per 100,000 per year. [13] Less frequently, blastomycosis also occurs in Africa, the Middle East, India, and western North America.
[10] It can occur as a mouth and skin type, lymphangitic type, multi-organ involvement type (particularly lungs), or mixed type. [1] [6] If there are mouth ulcers or skin lesions, the disease is likely to be widespread. [1] There may be no symptoms, or it may present with fever, sepsis, weight loss, large glands, or a large liver and spleen. [4 ...
Blastomyces dermatitidis is the causal agent of blastomycosis, a potentially very serious disease that typically begins with a characteristically subtle pneumonia-like infection that may progress, after 1–6 months, to a disseminated phase that causes lesions to form in capillary beds throughout the body, most notably the skin, internal organs, central nervous system and bone marrow.
Some types such as blastomycosis, cryptococcus, coccidioidomycosis and histoplasmosis, affect people who live in or visit certain parts of the world. [18] Others such as aspergillosis , pneumocystis pneumonia , candidiasis , mucormycosis and talaromycosis , tend to affect people who are unable to fight infection themselves. [ 18 ]
The fungal infection Gilchrist's disease, more commonly known as blastomycosis, is named for him after he first mistook it as a protozoan disease before correctly identifying it as a fungal in origin.
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Cold abscess refers to an abscess that lacks the intense inflammation usually associated with infection. This may be associated with infections due to bacteria like Mycobacterium tuberculosis, the cause of tuberculosis, [1] and fungi like those from the genus Blastomyces, which cause blastomycosis, [2] that do not tend to stimulate acute inflammation.