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Bronchiolitis obliterans (BO), also known as obliterative bronchiolitis, constrictive bronchiolitis and popcorn lung, is a disease that results in obstruction of the smallest airways of the lungs (bronchioles) due to inflammation. [1] [6] Symptoms include a dry cough, shortness of breath, wheezing and feeling tired. [1]
Infant prematurity is the factor most commonly associated with pulmonary hemorrhage. Other associated factors are those that predisposed to perinatal asphyxia or bleeding disorders, including toxemia of pregnancy, maternal cocaine use, erythroblastosis fetalis, breech delivery, hypothermia, infection (like pulmonary tuberculosis), Infant respiratory distress syndrome (IRDS), administration of ...
Lung function testing is used for the assessment and monitoring of functional impairment due to bronchiectasis. These tests may include spirometry and walking tests. [ 39 ] Obstructive lung impairment is the most common finding but restrictive lung impairment can be seen in advanced disease.
preventing further damage and allow full recovery to the lung. Pulmonary edema can cause permanent organ damage, and when sudden (acute), can lead to respiratory failure or cardiac arrest due to hypoxia. [7] The term edema is from the Greek οἴδημα (oidēma, "swelling"), from οἰδέω (oidéō, "(I) swell"). [8] [9]
Air flow in air passages can get restricted in three ways: [3] a spasmodic state of the smooth muscles in bronchi and bronchioles; an inflammation in the middle layers of the bronchi and bronchioles; excessive production of mucus. The bronchial spasm is due to the activation of parasympathetic nervous system.
Blood oxygen levels fall and carbon dioxide rises, resulting in rising blood acid levels and hypoxia. Structural immaturity, as manifested by a decreased number of gas exchange units and thicker walls, also contributes to the disease process. Therapeutic oxygen and positive-pressure ventilation, while potentially life-saving, can damage the lung.
The vascular resistance increases in the contused part of the lung, leading to a decrease in the amount of blood that flows into it, [38] directing blood to better-ventilated areas. [27] Although reducing blood flow to the unventilated alveoli is a way to compensate for the fact that blood passing unventilated alveoli is not oxygenated, [ 27 ...
In BAE, both bronchial mucosal necrosis and pulmonary infarction seldom occur. [1] It is presumed that this is because the pulmonary circulation is dually controlled by the bronchial artery and the pulmonary artery; and even if the blood flow in the bronchial artery is lost, blood flow from the pulmonary artery is slightly maintained. [1]