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Lithium is readily absorbed from the gastrointestinal tract. [5] It is distributed to the body with higher levels in the kidney, thyroid, and bone as compared to other tissues. Since lithium is almost exclusively excreted by the kidneys, people with preexisting chronic kidney disease are at high risk of developing lithium intoxication. [13]
These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Certain lithium compounds, also known as lithium salts, are used as psychiatric medication, [5] primarily for bipolar disorder and for major depressive disorder. [5] Lithium is taken orally (by mouth). [5] Common side effects include increased urination, shakiness of the hands, and increased thirst. [5]
Most of the adverse effects of Wellbutrin are mild and transient, although a small percentage of people who use this medication experience more severe or longer-lasting side effects. Common side ...
During the first several weeks of taking escitalopram, as your body is getting used to the new medication, you may experience an array of side effects. While serious side effects exist, most are ...
Approximately 15–50% of people who suddenly stop an antidepressant develop antidepressant discontinuation syndrome. [7] [2] [3] [4] The condition is generally not serious, [2] though about half of people with symptoms describe them as severe. [4] Many restart antidepressants due to the severity of the symptoms. [4]
Potential side effects from lithium include gastrointestinal upset, tremor, sedation, excessive thirst, frequent urination, cognitive problems, impaired motor coordination, hair loss, and acne. [3] Excessive levels of lithium can be harmful to the kidneys, and increase the risk of side effects in general.
Hepatotoxicity, dermatological side effects, and abuse potential. [7] Aminopyrine: 1999 France, Thailand Risk of agranulocytosis and severe acne. [3] Amobarbital: 1980 Norway Risk of barbiturate toxicity. [3] Amoproxan: 1970 France Dermatologic and ophthalmic toxicity. [3] Anagestone acetate: 1969 Germany Animal carcinogenicity. [3] Antrafenine ...