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The protein encoded by this gene is an integral membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate circulating iron uptake by regulating the interaction of the transferrin receptor with transferrin.
This mutation is associated with diverse health issues, however H63D syndrome is the only known specific expression of a homozygous HFE-H63D mutation to date. The homozygous HFE-H63D mutation is the cause of classic and treatable hemochromatosis in only 6.7% of its carriers. [25] H63D syndrome is independently a distinct entity, and the ...
Haemochromatosis is protean in its manifestations, i.e., often presenting with signs or symptoms suggestive of other diagnoses that affect specific organ systems.Many of the signs and symptoms below are uncommon, and most patients with the hereditary form of haemochromatosis do not show any overt signs of disease nor do they have premature morbidity, if they are diagnosed early, but, more ...
HFE (gene), a gene that encodes the Human hemochromatosis protein; Hello from Earth, an interstellar radio message; Hidden Field Equations, a cryptosystem; H-parameter model (h FE), the current gain of a bipolar junction transistor; Human factors engineering; Hydrofluoroether, a solvent
Vua tiếng Việt (lit. ' King of Vietnamese ' ) is a Vietnamese television quiz show featuring Vietnamese vocabulary and language, produced by Vietnam Television . [ 1 ] [ 2 ] The programme is aired on 8:30 pm every Friday on VTV3, starting from 10 September 2021, with the main host Nguyễn Xuân Bắc.
The common MTHFR deficiencies are usually asymptomatic, although the 677T variant can cause a mildly increased risk of some diseases. [citation needed]For individuals homozygous in the 677T variant, there is a mildly elevated risk of thromboembolism (odds ratio 1.2), [4] and stroke (odds ratio 1.26). [5]
A shipwrecked Chinese blown to Vietnam by the wind, Pan Dinggui in his book "Annan ji you" said that the Trinh restored the Le dynasty to power after Vietnam was struck by disease, thunder and winds when the Le was dethroned when they initially could not find Le and Tran dynasty royals to restore to the throne when he was in Vietnam in 1688.
In the song "Mother's Legacy" (Gia tài của mẹ), Trinh sings about the Vietnamese experience of the Vietnam War: [11] He laments that the 1,000 years of Vietnam's subjugation to Chinese imperial rule, the 100 years of subjugation to French colonial rule, and the ongoing civil war, together have left a sad legacy of graveyards, parched ...