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  2. Upstream and downstream (DNA) - Wikipedia

    en.wikipedia.org/wiki/Upstream_and_downstream_(DNA)

    Each strand of DNA or RNA has a 5' end and a 3' end, so named for the carbon position on the deoxyribose (or ribose) ring. By convention, upstream and downstream relate to the 5' to 3' direction respectively in which RNA transcription takes place. [1] Upstream is toward the 5' end of the RNA molecule, and downstream is toward the 3

  3. Eukaryotic transcription - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_transcription

    Targeting the rate-limiting initial step is the most efficient in terms of energy costs for the cell. Transcription initiation is regulated by cis-acting elements (enhancers, silencers, isolators) within the regulatory regions of the DNA, and sequence-specific trans-acting factors that act as activators or repressors. [1]

  4. Directionality (molecular biology) - Wikipedia

    en.wikipedia.org/wiki/Directionality_(molecular...

    (See also upstream and downstream.) Directionality is related to, but different from, sense. Transcription of single-stranded RNA from a double-stranded DNA template requires the selection of one strand of the DNA template as the template strand that directly interacts with the nascent RNA due to complementary sequence. The other strand is not ...

  5. DNA extraction - Wikipedia

    en.wikipedia.org/wiki/DNA_extraction

    The first isolation of deoxyribonucleic acid (DNA) was done in 1869 by Friedrich Miescher. [1] DNA extraction is the process of isolating DNA from the cells of an organism isolated from a sample, typically a biological sample such as blood, saliva, or tissue. It involves breaking open the cells, removing proteins and other contaminants, and ...

  6. Upstream and downstream - Wikipedia

    en.wikipedia.org/wiki/Upstream_and_downstream

    Upstream and downstream (DNA), determining relative positions on DNA; Upstream and downstream (transduction) determining temporal and mechanistic order of cellular and molecular events of signal transduction

  7. Promoter (genetics) - Wikipedia

    en.wikipedia.org/wiki/Promoter_(genetics)

    In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may encode a protein , or can have a function in and of itself, such as tRNA or rRNA.

  8. 7 Travel Hacks To Save Money on Spring Break 2025 - AOL

    www.aol.com/7-travel-hacks-save-money-220011947.html

    Planning a tropical getaway this Spring Break but don’t want to break the bank?Believe it or not, there are all sorts of tricks that could decrease the cost of your 2025 vacation.

  9. Regulatory sequence - Wikipedia

    en.wikipedia.org/wiki/Regulatory_sequence

    An active enhancer regulatory sequence of DNA is enabled to interact with the promoter DNA regulatory sequence of its target gene by formation of a chromosome loop. This can initiate messenger RNA (mRNA) synthesis by RNA polymerase II (RNAP II) bound to the promoter at the transcription start site of the gene. The loop is stabilized by one ...