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Regeneration in biology is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. [1] Every species is capable of regeneration, from bacteria to humans.
Epimorphosis is defined as the regeneration of a specific part of an organism in a way that involves extensive cell proliferation of somatic stem cells, [1] dedifferentiation, and reformation, [2] as well as blastema formation. [3]
The four types of regeneration are epimorphosis, stem cell mediated regeneration, morphallaxis, and compensatory regeneration (compensatory hyperplasia). Epimorphosis occurs when other adult cells in a damaged tissue undergo dedifferentiation and then divide to form an undifferentiated mass of tissue, this new mass encompasses the mass of ...
Regeneration (biology), the ability to recreate lost or damaged cells, tissues, organs and limbs; Regeneration (ecology), the ability of ecosystems to regenerate biomass, using photosynthesis; Regeneration in humans, the ability of humans to recreate, or induce the regeneration of, lost tissue
Regeneration in humans is the regrowth of lost tissues or organs in response to injury. This is in contrast to wound healing, or partial regeneration, which involves closing up the injury site with some gradation of scar tissue.
Morphogenesis can take place also in a mature organism, such as in the normal maintenance of tissue by stem cells or in regeneration of tissues after damage. Cancer is an example of highly abnormal and pathological tissue morphogenesis.
The existing epithelial cells can replicate, and, using the basement membrane as a guide, eventually bring the kidney back to normal. After regeneration is complete, the damage is undetectable, even microscopically. [citation needed] Healing must happen by repair in the case of injury to cells that are unable to regenerate (e.g. neurons).
A blastema (Greek βλάστημα, "offspring" [1]) is a mass of cells capable of growth and regeneration into organs or body parts. The changing definition of the word "blastema" has been reviewed by Holland (2021). [2] A broad survey of how blastema has been used over time brings to light a somewhat involved history.