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Elephantiasis, often incorrectly called elephantitis, is the enlargement and hardening of limbs or body parts due to tissue swelling . [ 1 ] [ 2 ] It is characterised by edema, hypertrophy , and fibrosis of skin and subcutaneous tissues, due to obstruction of lymphatic vessels ( lymphedema ). [ 2 ]
Podoconiosis, also known as nonfilarial elephantiasis, [1] is a disease of the lymphatic vessels of the lower extremities that is caused by chronic exposure to irritant soils. It is the second most common cause of tropical lymphedema after lymphatic filariasis , [ 2 ] and it is characterized by prominent swelling of the lower extremities, which ...
Lymphatic filariasis is a human disease caused by parasitic worms known as filarial worms. [2] [3] Usually acquired in childhood, it is a leading cause of permanent disability worldwide, impacting over a hundred million people and manifesting itself in a variety of severe clinical pathologies [6] [7] While most cases have no symptoms, some people develop a syndrome called elephantiasis, which ...
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Elephantiasis nostras is a disease that usually affects the lower legs or scrotum. [1] Swelling is accompanied by rough nodules or wart-like plaques on the skin. If the disease is not treated, it eventually results in pain and immobility.
Lymphedema is most frequently a complication of cancer treatment or parasitic infections, but it can also be seen in a number of genetic disorders. Tissues with lymphedema are at high risk of infection because the lymphatic system has been compromised. [3] Though incurable and progressive, a number of treatments may improve symptoms. [2]
The most obvious sign of infection, elephantiasis, is the enlargement of the limbs–usually the legs. A late complication of infection, elephantiasis is a form of lymphedema and is caused by repeated inflammation of the lymphatic vessels. Repeated inflammatory reactions causes vessel dilation and thickening of the affected lymphatic vessels ...