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Hypoprolactinemia is associated with ovarian dysfunction in women, [3] [4] and, in men, metabolic syndrome, [5] anxiety symptoms, [5] arteriogenic erectile dysfunction, [6] premature ejaculation, [5] oligozoospermia (low concentration of sperm in semen), asthenospermia (reduced sperm motility), hypofunction of seminal vesicles, and hypoandrogenism. [7]
Prolactin has a wide variety of effects. It stimulates the mammary glands to produce milk (): increased serum concentrations of prolactin during pregnancy cause enlargement of the mammary glands and prepare for milk production, which normally starts when levels of progesterone fall by the end of pregnancy and a suckling stimulus is present.
It therefore follows that there may also be symptoms of the female athlete triad, eating disorders, low bone density, or osteoporosis. [11] Some may willing consume insufficient calories in conjunction with or independent of an underlying eating disorder, meaning that women with FHA may be normal weight or underweight.
In women, prolactin is the hormone that regulates milk production. High prolactin levels can lead to a bunch of issues like infertility, intimate problems and bone loss, as well as breast pain and ...
Additionally, it is thought that depression, drug addiction, high levels of prolactin, low testosterone, and uses of certain medications might play a role in inhibiting dopamine. A spinal cord injury or chronic fatigue syndrome might also occasionally cause this disorder. [ 2 ]
Unlike women, who most commonly have microprolactinomas, men usually present with macroprolactinomas, and their serum prolactin levels are generally much higher than those observed in women. [ 13 ] Long-term hyperprolactinaemia can lead to detrimental changes in bone metabolism as a result of hypoestrogenism and hypoandrogenism .
The failure to breastfeed and amenorrhea no more periods, were seen as the syndrome (a collection of symptoms), but we now view Sheehan's as the pituitary failing to secrete 1-5 of the 9 hormones that it normally produces (the anterior (front) lobe of the pituitary produces FSH, LH, prolactin, ACTH (Adreno-cortico-trophic hormone),TSH (Thyroid ...
Changes in levels of certain hormones, such as prolactin or luteinizing hormone (LH) Mental health issues, such as depression, stress or anxiety Inflammation affecting the prostate gland or urethra