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The report says researchers should not use race as a proxy for describing human genetic variation. Race is a social concept, but it is often used in genomics and genetics research as a surrogate for describing human genetic differences, which is misleading, inaccurate, and harmful. ^ Goodman AH (2020).
Human genetic variation is the genetic differences in and among populations. There may be multiple variants of any given gene in the human population (alleles), a situation called polymorphism. No two humans are genetically identical. Even monozygotic twins (who develop from one zygote) have infrequent genetic differences due to mutations ...
In it, Lewontin presented an analysis of genetic diversity amongst people from different conventionally-defined races. His main finding, that there is more genetic variation within these populations than between them, [2] is considered a landmark in the study of human genetic variation and contributed to the abandonment of race as a scientific ...
Recent interest in race-based medicine, or race-targeted pharmacogenomics, has been fueled by the proliferation of human genetic data which followed the decoding of the human genome in the first decade of the twenty-first century. There is an active debate among biomedical researchers about the meaning and importance of race in their research.
He found that the majority of the total genetic variation between humans (i.e., of the 0.1% of DNA that varies between individuals), 85.4%, is found within populations, 8.3% of the variation is found between populations within a "race", and only 6.3% was found to account for the racial classification. Numerous later studies have confirmed his ...
None. In human genetics, the Mitochondrial Eve (more technically known as the Mitochondrial-Most Recent Common Ancestor, shortened to mt-Eve or mt-MRCA) is the matrilineal most recent common ancestor (MRCA) of all living humans. In other words, she is defined as the most recent woman from whom all living humans descend in an unbroken line ...
New interest in human biological variation has resulted in a resurgence of the use of race in biomedicine. [ 91 ] The main impetus for this development is the possibility of improving the prevention and treatment of certain diseases by predicting hard-to-ascertain factors, such as genetically conditioned health factors, based on more easily ...
A wide range of methods have been developed to assess the structure of human populations with the use of genetic data. Early studies of within and between-group genetic variation used physical phenotypes and blood groups, with modern genetic studies using genetic markers such as Alu sequences, short tandem repeat polymorphisms, and single nucleotide polymorphisms (SNPs), among others. [11]