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  2. Bottom–up and top–down design - Wikipedia

    en.wikipedia.org/wiki/Bottom–up_and_topdown...

    Top–down methods were favored in software engineering until the late 1980s, [3] and object-oriented programming assisted in demonstrating the idea that both aspects of top-down and bottom-up programming could be used. Modern software design approaches usually combine top–down and bottomup approaches. Although an understanding of the ...

  3. Nanomanufacturing - Wikipedia

    en.wikipedia.org/wiki/Nanomanufacturing

    Nanomanufacturing is both the production of nanoscaled materials, which can be powders or fluids, and the manufacturing of parts "bottom up" from nanoscaled materials or "top down" in smallest steps for high precision, used in several technologies such as laser ablation, etching and others. Nanomanufacturing differs from molecular manufacturing ...

  4. Bottom-up proteomics - Wikipedia

    en.wikipedia.org/wiki/Bottom-up_proteomics

    Bottom-up proteomics is a common method to identify proteins and characterize their amino acid sequences and post-translational modifications by proteolytic digestion of proteins prior to analysis by mass spectrometry. [1][2] The major alternative workflow used in proteomics is called top-down proteomics where intact proteins are purified prior ...

  5. Top-down - Wikipedia

    en.wikipedia.org/wiki/Top-down

    Top-down processing, in Pattern recognition (psychology) Computing. Top-down and bottom-up design of information ordering; Top-down parsing, a parsing strategy beginning at the highest level of the parse tree Top-down parsing language, an analytic formal grammar to study top-down parsers; Top-down perspective, a camera angle in computer and ...

  6. Software development process - Wikipedia

    en.wikipedia.org/wiki/Software_development_process

    In 1988, Barry Boehm published a formal software system development "spiral model," which combines some key aspects of the waterfall model and rapid prototyping methodologies, in an effort to combine advantages of top-down and bottom-up concepts. It provided emphasis on a key area many felt had been neglected by other methodologies: deliberate ...

  7. Top-down proteomics - Wikipedia

    en.wikipedia.org/wiki/Top-down_proteomics

    Top-down vs bottom-up proteomics. Top-down proteomics is a method of protein identification that either uses an ion trapping mass spectrometer to store an isolated protein ion for mass measurement and tandem mass spectrometry (MS/MS) analysis [1] [2] or other protein purification methods such as two-dimensional gel electrophoresis in conjunction with MS/MS. [3] Top-down proteomics is capable ...

  8. Book design - Wikipedia

    en.wikipedia.org/wiki/Book_design

    Book design is the art of incorporating the content, style, format, design, and sequence of the various components and elements of a book into a coherent unit. In the words of renowned typographer Jan Tschichold (1902–1974), book design, "though largely forgotten today, [relies upon] methods and rules upon which it is impossible to improve ...

  9. Structure chart - Wikipedia

    en.wikipedia.org/wiki/Structure_Chart

    As a design tool, they aid the programmer in dividing and conquering a large software problem, that is, recursively breaking a problem down into parts that are small enough to be understood by a human brain. The process is called top-down design, or functional decomposition. Programmers use a structure chart to build a program in a manner ...