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  2. Bumetanide - Wikipedia

    en.wikipedia.org/wiki/Bumetanide

    Bumetanide is a loop diuretic and works by decreasing the reabsorption of sodium by the kidneys. The main difference between bumetanide and furosemide is in their bioavailability and potency. About 60% of furosemide is absorbed in the intestine, and there are substantial inter- and intraindividual differences in bioavailability (range 10-90%).

  3. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    However, for torsemide and bumetanide, their oral bioavailability is consistently higher than 90%. Torsemide has a longer half life in heart failure patients (6 hours) than furosemide (2.7 hours). A 40 mg dose of furosemide is clinically equivalent to a 20 mg dose of torsemide and to a 1 mg dose of bumetanide. [6]

  4. Metolazone - Wikipedia

    en.wikipedia.org/wiki/Metolazone

    This lowers blood pressure and prevents excess fluid accumulation in heart failure. Metolazone is sometimes used together with loop diuretics such as furosemide or bumetanide, but these highly effective combinations can lead to dehydration and electrolyte abnormalities. It was patented in 1966 and approved for medical use in 1974. [1]

  5. Drugs in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Drugs_in_pregnancy

    Heartburn is a common symptom of late term pregnancy during which up to 80% of pregnant women have experienced it by the end of their third trimester. [12] Heartburn often indicates the development of gastro-esophageal reflux disease (GERD), where the lower esophageal sphincter relaxes due to elevated progesterone levels causing increased ...

  6. Furosemide - Wikipedia

    en.wikipedia.org/wiki/Furosemide

    The action on the distal tubules is independent of any inhibitory effect on carbonic anhydrase or aldosterone; it also abolishes the corticomedullary osmotic gradient and blocks negative, as well as positive, free water clearance. Because of the large NaCl absorptive capacity of the loop of Henle, diuresis is not limited by the development of ...

  7. Should You Stock Up On The Abortion Pill Now? Here's What ...

    www.aol.com/stock-abortion-pill-now-heres...

    After the 2024 election, women’s reproductive rights are front and center of the news cycle, once again.. According to reports, there has already been a surge in demand for mifepristone, a.k.a ...

  8. GM to retreat from robotaxis and stop funding its Cruise ...

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    General Motors said Tuesday it will retreat from the robotaxi business and stop funding its money-losing Cruise autonomous vehicle unit. Instead the Detroit automaker will focus on development of ...

  9. Torasemide - Wikipedia

    en.wikipedia.org/wiki/Torasemide

    Use is not recommended in pregnancy or breastfeeding. [2] It works by decreasing the reabsorption of sodium by the kidneys. [1] Torasemide was patented in 1974 and came into medical use in 1993. [3] It is on the World Health Organization's List of Essential Medicines. [4] It is available as a generic medication. [2]

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