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Equine polysaccharide storage myopathy (EPSM, PSSM, EPSSM) is a hereditary glycogen storage disease of horses that causes exertional rhabdomyolysis.It is currently known to affect the following breeds American Quarter Horses, American Paint Horses, Warmbloods, Cobs, Dales Ponies, Thoroughbreds, Arabians, New Forest ponies, and a large number of Heavy horse breeds.
However, any horse that can store excess amounts of glycogen, usually genetic, can develop this form of ER. [1] Recurrent Exertional Rhabdomyolysis (RER) is commonly found in breeds that are high strung such as Arabians and thoroughbreds. However, any horse can develop this type of ER if it displays abnormal muscle contractions. [1]
The diagnosis of hypokalemia (not enough potassium) can be suspected when there is a history of diarrhoea or malnutrition. Loop diuretics may also contribute. The electrocardiogram may show flattening of T waves and prominent U waves. Hypokalemia is an important cause of acquired long QT syndrome, and may predispose the patient to torsades de ...
Horses can develop a number of muscle disorders, many of which may progress to rhabdomyolysis. Of these, some cause isolated attacks of rhabdomyolysis (e.g., dietary deficiency in vitamin E and selenium , poisoning associated with pasture or agricultural poisons such as organophosphates ), while others predispose to exertional rhabdomyolysis (e ...
Additionally, horses with a hind limb lameness will tend to reduce the degree of leg use. To do so, some horses will reduce the contraction time of the gluteals on the side of the lame leg, leading to a "hip roll" or "hip dip" and appearance that the hip drops a greater degree on the side of the lame leg. [10]
Type and severity of injury determines the duration and degree of rest required. Aggressive limitations of activity may be required in cases of fracture. Horses are kept tied for the several-month duration of healing, to prevent them from lying down and potentially re-injuring the bone while trying to stand.
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A handful of published reports describe individuals with severe hypokalemia related to chronic extreme consumption (4–10 L/day) of cola. [20] The hypokalemia is thought to be from the combination of the diuretic effect of caffeine [21] and copious fluid intake, although it may also be related to diarrhea caused by heavy fructose ingestion ...
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