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Oral exemestane 25 mg/day for 2–3 years of adjuvant therapy was generally more effective than 5 years of continuous adjuvant tamoxifen in the treatment of postmenopausal women with early-stage estrogen receptor-positive/unknown receptor status breast in a large well-designed [citation needed] trial. Preliminary data from the open-label TEAM ...
But “vitamin D3 is more bioavailable (a.k.a has a stronger ability to be absorbed and used in the body), which is why people tend to prefer vitamin D3," says JoAnn Manson, M.D., MPH, DrPH, a ...
[5] [6] Tamoxifen treatment is also used for the treatment of osteoporosis and blood lipids in postmenopausal women. Adverse effects of tamoxifen include hot flashes and an increase in the risk of developing endometrial cancer compared to women of similar age. [6] [4] Toremifene, a chlorinated tamoxifen derivative developed to avoid hepatic ...
The effects of tamoxifen on breast cancer Ki-67 expression, sex hormone-binding globulin (SHBG) levels, and IGF-1 levels are dose-dependent across a dosage range of 1 to 20 mg/day in women with breast cancer. [84] Tamoxifen has been found to decrease insulin-like growth factor 1 (IGF-1) levels by 17 to 38% in women and men. [85] Suppression of ...
Both vitamin D2 and D3 are good, but “D3 has better bioavailablilty,” says Dr. Manson, meaning that it’s more easily used by your body. But that doesn’t mean any old brand will do.
Since vitamin D is a fat-soluble vitamin, too much can put you at serious risk for toxicity including adverse side effects like kidney stones and high calcium levels in the blood. Our experts say ...
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