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Mohs surgery is the gold standard method for obtaining complete margin control during removal of a skin cancer (complete circumferential peripheral and deep margin assessment - CCPDMA) using frozen section histology. [1] CCPDMA or Mohs surgery allows for the removal of a skin cancer with very narrow surgical margin and a high cure rate.
Skin biopsy is a biopsy technique in which a skin lesion is removed to be sent to a pathologist to render a microscopic diagnosis.It is usually done under local anesthetic in a physician's office, and results are often available in 4 to 10 days.
As the CCPDMA surgery is frequently performed using frozen section pathology, immediate reporting of positive surgical margin is made, and the tumor can be completely removed in the same day. Traditional pathology processing is called "bread loafing", and only allows for the partial examination of the surgical margin.
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There are two major types of specimens submitted for surgical pathology analysis: biopsies and surgical resections. [1]A biopsy is a small piece of tissue removed primarily for the purposes of surgical pathology analysis, most often in order to render a definitive diagnosis.
The American College of Mohs Surgery (abbreviated as ACMS) is a membership-based organization of surgeons who are fellowship-trained (FACMS) in Mohs surgery, a technique that removes skin cancer in stages, one tissue layer at a time. The ACMS is the oldest and largest professional membership organization for Mohs surgeons. [2]
Eponymous surgical procedures are generally named after the surgeon or surgeons who performed or reported them first. In some instances they are named after the surgeon who popularised them or refined existing procedures, and occasionally are named after the patient who first underwent the procedure.
A 2009 meta-analysis of randomized controlled trials found a small difference in survival rates favoring wide excision of primary cutaneous melanomas, but these results were not statistically significant. [108] Mohs surgery has been reported with cure rate as low as 77% [109] and as high as 98.0% for melanoma-in-situ. [110]