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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    [229] [232] [233] The relationship between a single dose of spironolactone and plasma levels of canrenone, a major active metabolite of spironolactone, has been found to be linear across a dose range of 25 to 200 mg spironolactone. [195] Steady-state concentrations of spironolactone are achieved within 8 to 10 days of treatment initiation. [186 ...

  3. What is PCOS and why is it so hard to diagnose? Doctors ... - AOL

    www.aol.com/lifestyle/pcos-why-hard-diagnose...

    PCOS is a common reason why women have difficulty getting pregnant. Here are the symptoms to look out for. ... spironolactone, which blocks the effects of androgen on the skin; or prescription ...

  4. Hair Loss in Women: Everything You Need to Know - AOL

    www.aol.com/hair-loss-women-everything-know...

    Spironolactone. Spironolactone is a once-a-day tablet that can stop hair loss from progressing and encourage new hair growth. It’s especially useful for women with hormonal issues like PCOS.

  5. Polycystic ovary syndrome - Wikipedia

    en.wikipedia.org/wiki/Polycystic_ovary_syndrome

    Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.

  6. Yes, Experts Explain You Can Still Lose Weight If You Have PCOS

    www.aol.com/yes-experts-explain-still-lose...

    Aside from making healthy lifestyle improvements, Dr. Kumar says that PCOS is often treated with a variety of medications, including metformin, hormonal contraception, and spironolactone. You ...

  7. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    In one study, the threshold dose by subcutaneous injection for endometrial transformation in rabbits was 0.003–0.01 mg for cyproterone acetate, 0.1–0.3 mg for drospirenone, 0.5 mg for progesterone, and 10–20 mg for spironolactone. [119]

  8. 8 of the Best Hair Loss Treatments for Women - AOL

    www.aol.com/8-best-hair-loss-treatments...

    3. Spironolactone. Another androgen- and DHT-targeting treatment that can work for women is spironolactone. It’s sometimes prescribed off-label to treat hair loss that occurs due to polycystic ...

  9. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    However, spironolactone is metabolized to three active metabolites, which give it prolonged activity (13.8 – 16. 5 hours). Spironolactone has a long half-life and is excreted 47-51% through kidneys. Patients with chronic kidney disease therefore require close monitoring when taking the drug. Spironolactone is also eliminated through feces (35-41%

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