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Bulk-forming laxatives, also known as roughage, are substances, such as fiber in food and hydrophilic agents in over-the-counter drugs, that add bulk and water to stools so they can pass more easily through the intestines (lower part of the digestive tract). [2] Properties. Site of action: small and large intestines; Onset of action: 12–72 hours
Bulk-forming laxatives: ... Osmotic laxatives: Products such as Miralax (polyethylene glycol) pull water from other parts of the body and into the colon. This extra water adds volume and pressure ...
Side effects may include increased bowel gas, abdominal pain, and nausea. [3] Rare but serious side effects may include an abnormal heartbeat, seizures, and kidney problems. [8] Use appears to be safe during pregnancy. [9] [3] It is classified as an osmotic laxative: [4] It works by increasing the amount of water in the stool. [5]
Methyl cellulose is used to treat constipation and is classified as a bulk forming laxative. [2] It works by increasing the amount of stool present which improves intestinal contractions. [2] [3] Effects generally occur within three days. [2] It is taken orally with sufficient water. [3] Side effects may include abdominal pain. [3]
Common side effects include abdominal bloating and cramps. [3] A potential exists for electrolyte problems as a result of the diarrhea it produces. [3] No evidence of harm to the fetus has been found when used during pregnancy. [3] It is generally regarded as safe during breastfeeding. [5] It is classified as an osmotic laxative. [6]
Sodium citrate saline is one of the most effective osmotic laxatives (secondary in action only to magnesium citrate). [8] Its laxative action is the result of osmotic imbalance that extracts bound water from stool and pulls it back into the large bowel. The increased water content softens the stool and stimulates the bowel to contract (move its ...
Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of episodic and chronic constipation and for the management of neurogenic bowel dysfunction, as well as part of bowel preparation before medical examinations, such as for a colonoscopy.
[5] [6] This compound is a stimulant laxative and increases peristalsis in the gut. [5] [7] Sodium picosulfate is typically prescribed in a combined formulation with magnesium citrate, an osmotic laxative. This combination is a highly effective laxative, often prescribed to patients for bowel cleansing prior to colonoscopies. [5] [8]
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