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It binds to α 1 and α 2 adrenergic receptors [11] in the nasal mucosa. Due to its sympathomimetic effects, it should not be used by people with high blood pressure, or other heart problems. Extended usage of xylometazoline can result in decreased effectiveness or a buildup of tolerance against the drug. [12]
Women are taking the over-the-counter decongestant Mucinex, claiming the active ingredient, guaifenesin, helped to increase their fertility — and get pregnant.
Decongestants are often used in conjunction with cold medications or to combat pregnancy rhinitis in pregnant women. Common decongestants include pseudoephedrine and phenylephrine . [ 14 ] Pseudoephedrine is an alpha-adrenergic receptor agonist that enacts a vasoconstrictive effect to reduce airflow resistance in the nasal cavity and allow ...
Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations. [1] It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus. It was patented in 1961 and came into medical use in 1962. [2]
Levmetamfetamine, also known as l-desoxyephedrine or levomethamphetamine, and commonly sold under the brand name Vicks VapoInhaler among others, is an optical isomer of methamphetamine primarily used as a topical nasal decongestant. [2] It is used to treat nasal congestion from allergies and the common cold. [7]
The FDA's nasal decongestants drug list, or monograph, has not been updated since 1995. The process for changing a monograph has traditionally taken years or decades, requiring multiple rounds of ...
Pseudoephedrine is the most common oral decongestant alternative, but since it has potential for abuse, you’ll likely need to ask a pharmacist for help accessing it behind the counter.
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives. [5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant. [5]
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