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Common side effects include gastrointestinal effects such as nausea, vomiting, and diarrhea, as well as headache and insomnia. Postmarketing surveillance has revealed a variety of relatively rare but serious adverse effects associated with all members of the fluoroquinolone antibacterial class.
According to Forbes, there have been 45,000 reported cases of side effects related to fluoroquinolones. 23.1 million patients filled prescriptions for oral flouroquinolones in 2011.
Ciprofloxacin, like other fluoroquinolones, is known to trigger seizures or lower the seizure threshold, and may cause other central nervous system adverse effects.
Adverse effects are typically mild to moderate. However, severe, disabling, and potentially irreversible adverse effects sometimes occur, and for this reason it is recommended that use of fluoroquinolones be limited. Prominent among these are adverse effects that became the subject of a black box warning by the FDA in 2016. [9]
On occasion, serious adverse effects occur. [27] Common side-effects include gastrointestinal effects such as nausea, vomiting, and diarrhea, as well as headache and insomnia. The overall rate of adverse events in patients treated with fluoroquinolones is roughly similar to that seen in patients treated with other antibiotic classes.
Clinafloxacin is an investigational fluoroquinolone antibiotic. Despite its promising antibiotic activity, the clinical development of clinafloxacin has been hampered by its risk for inducing serious side effects.
Common side effects include diarrhea, dizziness, and headache. [4] Severe side effects may include spontaneous tendon ruptures, nerve damage, and worsening of myasthenia gravis. [4] Safety of use in pregnancy and breastfeeding is unclear. [6] Moxifloxacin is in the fluoroquinolone family of medications. [4]
1 Side effects. 2 Contraindications. ... Gatifloxacin (brand names Gatiflo, Tequin, and Zymar) is an antibiotic of the fourth-generation fluoroquinolone family, [1] ...