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eNOS is a dimer containing two identical monomers of 140 kD constituted by a reductase domain, which displays binding sites for nicotinamide adenine dinucleotide phosphate (NADPH), flavin mononucleotide (FMN), and flavin adenine dinucleotide (FAD), and an oxidase domain, which displays binding sites for heme group, zinc, the cofactor tetrahydrobiopterin (), and the substrate L-arginine. [13]
Nitric oxide is mediated in mammals by the calcium-calmodulin controlled isoenzymes eNOS (endothelial NOS) and nNOS (neuronal NOS). [2] The inducible isoform, iNOS, involved in immune response, binds calmodulin at physiologically relevant concentrations, and produces NO as an immune defense mechanism, as NO is a free radical with an unpaired ...
Biological functions of nitric oxide are roles that nitric oxide plays within biology. Nitric oxide (nitrogen monoxide) is a molecule and chemical compound with chemical formula of N O . In mammals including humans, nitric oxide is a signaling molecule involved in several physiological and pathological processes. [ 1 ]
Mercury-Atlas 5 was an American spaceflight of the Mercury program.It was launched on November 29, 1961, with Enos, a chimpanzee, aboard.The craft orbited the Earth twice and splashed down about 200 miles (320 km) south of Bermuda, and Enos became the first primate from the United States and the third great ape to orbit the Earth.
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Enos being prepared for insertion into the Mercury-Atlas 5 capsule in 1961. Enos’ space capsule during the Mercury-Atlas 5 mission, on display at the Museum of Life and Science, in Durham, North Carolina. Enos (born about 1957 – died November 4, 1962) was a chimpanzee launched into space by NASA, following his predecessor Ham.
Wikifunctions is a collaboratively edited catalog of computer functions to enable the creation, modification, and reuse of source code. [2] [3] It is closely related to Abstract Wikipedia, an extension of Wikidata to create a language-independent version of Wikipedia using its structured data.
Enos, Turkey, a town; Enos, a gossamer-winged butterfly genus; Enos (chimpanzee), a chimpanzee who launched into space; ENOS Rescue-System, an electronic rescue and locating system for use by divers at sea; eNOS, the enzyme endothelial nitric oxide synthase; Enos Strate, a character in the TV series The Dukes of Hazzard