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The company misbranded Depakote by promoting the drug to control agitation and aggression in elderly dementia patients and to treat schizophrenia when neither of these uses was FDA approved. This settlement figure represents resolution of other claims in addition to off-label promotion. [38]
Valproate may cause increased somnolence in the elderly. In a trial of valproate in elderly patients with dementia, a significantly higher portion of valproate patients had somnolence compared to placebo. In approximately one-half of such patients, there was associated reduced nutritional intake and weight loss. [4]
Depakote (valproic acid/sodium valproate) – an antiepileptic and mood stabilizer used to treat bipolar disorder, neuropathic pain and others; sometimes called an antimanic medication. Depakene is the trade name for the same drug prepared without sodium. Desyrel – an atypical antidepressant used to treat depression and insomnia
CVS and Walgreens. $10.7 billion. CVS and Walgreens have agreed to settle lawsuits brought against the companies by several states for their alleged role in the opioid crisis. CVS would pay nearly ...
Here's how to distinguish "sundowning"—agitation or confusion later in the day in dementia patients ... ‘Sundowning’ is a term that refers to behavior changes in people with dementia that ...
A new study found the biggest risk factors and predictors at 60 for dementia at 80. Neurologists weigh in on the research and share ways to prevent dementia.
Many patients will not develop these side effects, although there is still a significant possibility of risks associated with Antipsychotic usage. The percentage of patients affected by side effects like Tardive dyskinesia is significantly high and estimated to be a 20-50% prevalence. [1] [2]
Antibiotic use was not associated with an increased risk of cognitive impairment and dementia in healthy older adults, according to a recent study. ... “Elderly patients with infections often ...
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