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  2. Medicare now negotiating price of drug that costs $7,100 in ...

    www.aol.com/medicare-now-negotiating-price-drug...

    The annual list price of Bristol Myers Squibb’s Eliquis, a blood thinner that reduces the risk of stroke, is $7,100 in the US. But in Japan, it’s $940; in Canada, it’s $900; in Germany, it ...

  3. Medicare announces weight-loss drugs, including Ozempic ... - AOL

    www.aol.com/medicare-announces-15-drugs-price...

    Last year, Medicare reached agreements to lower prices on the 10 costliest drugs, including Eliquis, a blood thinner; Imbruvica, a blood cancer treatment; and NovoLog, a diabetes medication.

  4. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    The results of the negotiations were announced in August 2024, and Medicare's negotiated price for a 30-day supply of Eliquis is $231, a 56% decrease from the 2023 list price of $521. [43] The pricing is set to take effect in 2026. [44] [45]

  5. Diclofenac - Wikipedia

    en.wikipedia.org/wiki/Diclofenac

    Diclofenac, sold under the brand name Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. [6] [9] It can be taken orally (swallowed by mouth), inserted rectally as a suppository, injected intramuscularly, injected intravenously, applied to the skin topically, or through eye drops.

  6. Ozempic and Wegovy selected for next round of Medicare drug ...

    www.aol.com/ozempic-wegovy-selected-next-round...

    The list price for Ozempic is nearly $1,000 for a four-week supply, while Wegovy’s list price is roughly $1,350. ... arthritis and heart failure — such as Eliquis, Xarelto, Farxiga, Januvia ...

  7. Andexanet alfa - Wikipedia

    en.wikipedia.org/wiki/Andexanet_alfa

    Andexanet alfa, sold under the brand name Andexxa among others, is an antidote for the medications rivaroxaban and apixaban, when reversal of anticoagulation is needed due to uncontrolled bleeding. [8]

  8. Medicare targets popular weight loss drugs Ozempic, Wegovy ...

    www.aol.com/medicare-targets-popular-weight-loss...

    Medicare will seek to negotiate lower list prices for the blockbuster diabetes and weight loss drugs Ozempic and Wegovy and 14 other medications, a cost-saving move that would take effect in 2027.

  9. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    These two hydrogen bonds serve an important role directing the drug into the S1 and S4 subsites of FXa. The first hydrogen bond is a strong interaction which comes from the carbonyl oxygen of the oxazolidinone core of rivaroxaban. The second hydrogen bond is a weaker interaction and comes from the amino group of the clorothiophene carboxamide ...

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