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Triphenyl phosphate exhibits low acute toxicity by dermal or oral contact. [3] However, an increasing number of studies have linked exposure to TPhP with reproductive and developmental toxicity, neurotoxicity, metabolic disruption, endocrine effects, and genotoxicity. [6] [8] [9] TPhP has also been found to induce significant estrogenic activity.
Neurotoxic effects have also been linked to poisoning with OP pesticides causing four neurotoxic effects in humans: cholinergic syndrome, intermediate syndrome, organophosphate-induced delayed polyneuropathy (OPIDP), and chronic organophosphate-induced neuropsychiatric disorder (COPIND). These syndromes result after acute and chronic exposure ...
The most dangerous isomers are considered to be those containing ortho isomers, such as tri-ortho-cresyl phosphate, TOCP.The World Health Organization stated in 1990 that "Because of considerable variation among individuals in sensitivity to TOCP, it is not possible to establish a safe level of exposure" and "TOCP are therefore considered major hazards to human health."
The importance of ecopharmacovigilance is to monitor adverse effects of pharmaceuticals on humans through environmental exposure. [ citation needed ] Due to this relatively new field of science, researchers are continuously developing and understanding the impacts of pharmaceuticals in the environment and its risk on human and animal exposure.
The phosphorus-containing product is triphenylphosphine sulfide, Ph 3 PS. This reaction can be employed to assay the "labile" S 0 content of a sample, say vulcanized rubber. Triphenylphosphine selenide, Ph 3 PSe, may be easily prepared via treatment of PPh 3 with red (alpha-monoclinic) Se. Salts of selenocyanate, SeCN −, are used as the Se 0 ...
Chronic solvent-induced encephalopathy (CSE) is a condition induced by long-term exposure to organic solvents, often—but not always—in the workplace, that lead to a wide variety of persisting sensorimotor polyneuropathies and neurobehavioral deficits even after solvent exposure has been removed.
People are ingesting borax. Also known by its chemical name sodium borate decahydrate, borax is a salt typically used to kill ants and boost laundry detergent, among other household cleaning needs ...
Tris(1,3-dichloroisopropyl)phosphate (TDCPP) is a chlorinated organophosphate. Organophosphate chemicals have a wide variety of applications and are used as flame retardants , pesticides , plasticizers , and nerve gases .