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Along with the UK Cochrane Centre, the centre was originally created as part of the Information Systems Strategy of the NHS Research and Development Programme. The original aims of the centre were: To carry out and commission systematic reviews of research findings on the effectiveness and cost effectiveness of health care relevant to the NHS
The Clinical Practice Research Datalink (CPRD) is an observational and interventional research service that operates as part of the Department of Health and Social Care.It is jointly funded by the National Institute for Health and Care Research (NIHR) and the Medicines and Healthcare products Regulatory Agency (MHRA).
There is ongoing research into several potential benefits of candesartan beyond established indications. Candesartan is being investigated for its neuroprotective and anti-inflammatory properties. In an early Alzheimer's disease mouse model , candesartan significantly reduced amyloid burden and inflammation [ 22 ] and it is being examined as a ...
[8] Candesartan is used experimentally in preventive treatment of migraine. [9] [10] Lisinopril has been found less often effective than candesartan at preventing migraine. [11] The angiotensin II receptor blockers have differing potencies in relation to blood pressure control, with statistically differing effects at the maximal doses. [12]
Erythema ab igne (Latin for 'redness from fire') EAI, also known as hot water bottle rash, [2] is a skin condition caused by long-term exposure to heat (infrared radiation). [3] Prolonged thermal radiation exposure to the skin can lead to the development of reticulated erythema , hyperpigmentation , scaling, and telangiectasias in the affected ...
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
Rather than using a sequence of codes to capture activity, the new classification would have used a single alphanumeric code up to 15 characters long. When the NHS IA was superseded by NHS Connecting for Health (NHS CFH) in 2005, the project was placed on indefinite hold, and a program of annual revisions to OPCS-4 was implemented. Much of the ...
The main symptoms include several kinds of skin rash along with muscle weakness in both upper arms or thighs. [8] Although dermatomyositis is closely related to polymyositis and is sometimes assumed to be a complication of that disease, most patients with dermatomyositis develop skin symptoms before any muscle involvement.