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Hypertrophic cardiomyopathy screening is an assessment and testing to detect hypertrophic cardiomyopathy (HCM). [ 1 ] [ 2 ] It is a way of identifying HCM in immediate relatives of family members diagnosed with HCM, and athletes as part of a sports medical . [ 3 ]
Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which muscle tissues of the heart become thickened without an obvious cause. [8] The parts of the heart most commonly affected are the interventricular septum and the ventricles . [ 10 ]
Hypertrophic cardiomyopathy can be a deadly disease, and there was a time when it was largely untreatable. ... in the condition’s management—a change that has led to an ... piece of genetic ...
Causes range from non-serious to potentially fatal. [1] There are three broad categories of causes: heart or blood vessel related; reflex, also known as neurally mediated; and orthostatic hypotension. [1] Issues with the heart and blood vessels are the cause in about 10% and typically the most serious while neurally mediated is the most common. [1]
For example, the Valsalva maneuver (phase II) increases the intensity of hypertrophic cardiomyopathy murmurs, namely those of dynamic subvalvular left ventricular outflow obstruction. This is due to the decreased preload in this phase, worsening the obstruction and thus accentuating the murmur. [ 3 ]
Pulsus bisferiens, also known as biphasic pulse, is an aortic waveform with two peaks per cardiac cycle, a small one followed by a strong and broad one. [1] It is a sign of problems with the aorta, including aortic stenosis and aortic regurgitation, as well as hypertrophic cardiomyopathy causing subaortic stenosis.
Hypertrophic cardiomyopathy (HCM) is a common condition (prevalence >1:500) [41] characterized by abnormal thickening of the ventricular muscle, classically in the intraventricular septal wall. HCM is described as a disease of the sarcomere , because mutations in the contractile proteins of the sarcomere have been identified in about half of ...
In dilated cardiomyopathy the ventricles enlarge and weaken. [3] In restrictive cardiomyopathy the ventricle stiffens. [3] In many cases, the cause cannot be determined. [4] Hypertrophic cardiomyopathy is usually inherited, whereas dilated cardiomyopathy is inherited in about one third of cases. [4]
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