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  2. Drugs in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Drugs_in_pregnancy

    Loperamide has limited data on the impact it has on pregnancy, but there is an association with cardiovascular malformation in the first trimester. [14] [12] Atropine/diphenoxylate currently has insufficient evidence of teratogenicity in humans, but trials with animals showed evidence of teratogenic effects. [14]

  3. Azithromycin - Wikipedia

    en.wikipedia.org/wiki/Azithromycin

    Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. [10] This includes middle ear infections , strep throat , pneumonia , traveler's diarrhea , and certain other intestinal infections . [ 10 ]

  4. Pregnancy category - Wikipedia

    en.wikipedia.org/wiki/Pregnancy_category

    The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, ... at least in the first trimester. Group 8

  5. Spiramycin - Wikipedia

    en.wikipedia.org/wiki/Spiramycin

    Spiramycin is a macrolide antibiotic and antiparasitic. It is used to treat toxoplasmosis and various other infections of soft tissues.. Although used in Europe, Canada and Mexico, [1] spiramycin is still considered an experimental drug in the United States, but can sometimes be obtained by special permission from the FDA for toxoplasmosis in the first trimester of pregnancy. [2]

  6. Trimethoprim/sulfamethoxazole - Wikipedia

    en.wikipedia.org/wiki/Trimethoprim/sulfamethoxazole

    Its use during pregnancy is contraindicated, although it has been placed in Australian pregnancy category C. [13] Its use during the first trimester (during organogenesis) and 12 weeks prior to pregnancy has been associated with an increased risk of congenital malformations, especially malformations associated with maternal folic acid ...

  7. Maternal physiological changes in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Maternal_physiological...

    The heart rate increases, but generally not above 100 beats/ minute. Total systematic vascular resistance decreases by 20% secondary to the vasodilatory effect of progesterone. Overall, the systolic and diastolic blood pressure drops 10–15 mm Hg in the first trimester and then returns to baseline in the second half of pregnancy. [6]

  8. Obstetrics - Wikipedia

    en.wikipedia.org/wiki/Obstetrics

    The newer integrated screen (formerly called F.A.S.T.E.R for First And Second Trimester Early Results) can be done at 10 plus weeks to 13 plus weeks with an ultrasound of the fetal neck (thicker nuchal skin correlates with higher risk of Down syndrome being present) and two chemicals (analytes), pregnancy-associated plasma protein A and human ...

  9. Quinolone antibiotic - Wikipedia

    en.wikipedia.org/wiki/Quinolone_antibiotic

    Safety concerns exist for fluoroquinolone use during pregnancy, so they are contraindicated unless no other safe alternative antibiotic exists. [54] However, one meta-analysis looking at the outcome of pregnancies involving quinolone use in the first trimester found no increased risk of malformations. [55]

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