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It was first conceptualized by August Krogh in 1919 with the help of Agner Krarup Erlang to describe oxygen supply in living tissues from human blood vessels. [1] [2] Its applicability has been extended to various academic fields, and has been successful explaining drug diffusion, water transport, and ice formation in tissues. [3]
Gas is breathed at ambient pressure, and some of this gas dissolves into the blood and other fluids. Inert gas continues to be taken up until the gas dissolved in the tissues is in a state of equilibrium with the gas in the lungs (see saturation diving), or the ambient pressure is reduced until the inert gases dissolved in the tissues are at a higher concentration than the equilibrium state ...
Diffusion is also faster in smaller, lighter molecules of which helium is the extreme example. Diffusivity of helium is 2.65 times faster than nitrogen. [14] The partial pressure gradient, also known as the concentration gradient, can be used as a model for the driving mechanism of diffusion. The partial pressure gradient is the rate of ...
The Maxwell–Stefan diffusion (or Stefan–Maxwell diffusion) is a model for describing diffusion in multicomponent systems. The equations that describe these transport processes have been developed independently and in parallel by James Clerk Maxwell [ 1 ] for dilute gases and Josef Stefan [ 2 ] for liquids.
A diffusion model models data as generated by a diffusion process, whereby a new datum performs a random walk with drift through the space of all possible data. [2] A trained diffusion model can be sampled in many ways, with different efficiency and quality.
The oxygen–hemoglobin dissociation curve, also called the oxyhemoglobin dissociation curve or oxygen dissociation curve (ODC), is a curve that plots the proportion of hemoglobin in its saturated (oxygen-laden) form on the vertical axis against the prevailing oxygen tension on the horizontal axis. This curve is an important tool for ...
The Bohr effect increases the efficiency of oxygen transportation through the blood. After hemoglobin binds to oxygen in the lungs due to the high oxygen concentrations, the Bohr effect facilitates its release in the tissues, particularly those tissues in most need of oxygen. When a tissue's metabolic rate increases, so does its carbon dioxide ...
Reaction–diffusion systems are mathematical models that correspond to several physical phenomena. The most common is the change in space and time of the concentration of one or more chemical substances: local chemical reactions in which the substances are transformed into each other, and diffusion which causes the substances to spread out ...