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  2. Scopolamine - Wikipedia

    en.wikipedia.org/wiki/Scopolamine

    The effects of scopolamine were studied for use as a truth serum in interrogations in the early 20th century, [62] but because of the side effects, investigations were dropped. [63] In 2009, the Czechoslovak state security secret police were proven to have used scopolamine at least three times to obtain confessions from alleged antistate ...

  3. Hyoscine butylbromide - Wikipedia

    en.wikipedia.org/wiki/Hyoscine_butylbromide

    Hyoscine butylbromide, also known as scopolamine butylbromide [4] and sold under the brandname Buscopan among others, [5] is an anticholinergic medication used to treat abdominal pain, esophageal spasms, bladder spasms, biliary colic, [6] and renal colic. [7] [8] It is also used to improve excessive respiratory secretions at the end of life. [9]

  4. Truth serum - Wikipedia

    en.wikipedia.org/wiki/Truth_serum

    Amobarbital, one of the chemical compounds that can be used as a truth serum. Sedatives or hypnotics that alter higher cognitive function include ethanol, scopolamine, 3-quinuclidinyl benzilate, potent short or intermediate acting hypnotic benzodiazepines such as midazolam, flunitrazepam, and various short and ultra-short acting barbiturates, including sodium thiopental (commonly known by the ...

  5. Deliriant - Wikipedia

    en.wikipedia.org/wiki/Deliriant

    The antimuscarinic plant-based alkaloids scopolamine and atropine are also notorious for their characteristic hyperactive effects and ability to cause stark and dream-like hallucinations. [5] [21] The hallucinations themselves are often described by users as disturbing, unpleasant or dark in nature.

  6. Datura stramonium - Wikipedia

    en.wikipedia.org/wiki/Datura_stramonium

    All parts of Datura plants contain dangerous levels of the tropane alkaloids atropine, hyoscyamine, and scopolamine, all of which are classified as deliriants, or anticholinergics. [2] [9] The risk of fatal overdose is high among uninformed users, and many hospitalizations occur among recreational users who ingest the plant for its psychoactive ...

  7. Muscarinic antagonist - Wikipedia

    en.wikipedia.org/wiki/Muscarinic_antagonist

    However, scopolamine has greater effects on the central nervous system (CNS) than atropine due to its ability to cross the blood–brain barrier. [4] At higher-than-therapeutic doses, atropine and scopolamine cause CNS depression characterized by amnesia, fatigue, and reduction in rapid eye movement sleep.

  8. ‘Like going to the moon’: Why this is the world’s most ...

    www.aol.com/going-moon-why-world-most-120326810.html

    The Drake Passage, between the southern tip of South America and Antarctic, is infamous as one of the most dangerous journeys on the planet. But why is it so rough – and how can you cross safely?

  9. Psychoplastogen - Wikipedia

    en.wikipedia.org/wiki/Psychoplastogen

    The effects of psychedelics on neuroplasticity appear to be dependent on serotonin 5-HT 2A receptor activation, as they are abolished in 5-HT 2A receptor knockout mice. [7] Non-hallucinogenic serotonin 5-HT 2A receptor agonists, like tabernanthalog and lisuride , have also been found to increase neuroplasticity, and to a magnitude comparable to ...

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