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The criteria for an ideal drug carrier include maximum effect upon delivery of the drug to the target organ, evasion of the immune system of the body in the process of reaching the organ, retention of the therapeutic molecules from preparatory stages to the final delivery of the drug, and proper release of the drug for exertion of the intended ...
Nanocarriers are useful in the drug delivery process because they can deliver drugs to site-specific targets, allowing drugs to be delivered in certain organs or cells but not in others. Site-specificity is a major therapeutic benefit as it prevents drugs from being delivered to the wrong places.
Melt blowing is a conventional fabrication method of micro- and nanofibers where a polymer melt is extruded through small nozzles surrounded by high speed blowing gas. The randomly deposited fibers form a nonwoven sheet product applicable for filtration, sorbents, apparels and drug delivery systems.
To obtain nanotubes, the polymer/template system is cooled down to room temperature or the solvent is evaporated, yielding pores covered with solid layers. The resulting tubes can be removed by mechanical forces for tubes up to 10 μm in length, i.e., by just drawing them out from the pores or by selectively dissolving the template.
Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency. Recently, nanoparticles have aroused attention due to their potential ...
Electrospinning is a fiber production method that uses electrical force (based on Electrohydrodynamic [1] principals) to draw charged threads of polymer solutions for producing nanofibers with diameters ranging from nanometers to micrometers.
Nanofabrics research is an interdisciplinary effort involving bioengineering, [5] molecular chemistry, physics, electrical engineering, computer science, and systems engineering. [3] Applications of nanofabrics have the potential to revolutionize textile manufacturing [6] and areas of medicine such as drug delivery and tissue engineering. [7]
A drug carrier or drug vehicle is a substrate used in the process of drug delivery which serves to improve the selectivity, effectiveness, and/or safety of drug administration. [1] Drug carriers are primarily used to control the release of drugs into systemic circulation.