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Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. [10] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent ( dual antiplatelet therapy ). [ 10 ]
Prasugrel is a member of the thienopyridine class of ADP receptor inhibitors, like ticlopidine (trade name Ticlid) and clopidogrel (trade name Plavix). These agents reduce the aggregation ("clumping") of platelets by irreversibly binding to P2Y 12 receptors. Prasugrel inhibits platelet aggregation more rapidly, more consistently, and to a ...
Metabolism of ticlopidine, clopidogrel and prasugrel to an active metabolite. Clopidogrel is a prodrug that is metabolized by two pathways. In one of the pathway most of the dose of clopidogrel (85%) is hydrolyzed by esterases to an inactive carboxylic acid derivate and rapidly cleared via glucoridination followed by renal excretion.
Tired all the time: there’s a range of reasons you may feel constantly sleepy, but it’s important to identify the cause and try to counteract it (Getty) It’s that time of year again.
While high blood pressure doesn’t always cause symptoms, there are many potential ways that it can lead to fatigue, including medication side effects and increased workload on your heart ...
Does Ozempic make you tired? An endocrinologist explains if the type 2 diabetes drug, sometimes used for weight loss, leads to fatigue and other side effects.
Physostigmine is one of only a few drugs that can be used as an antidote for anticholinergic poisoning. Nicotine also counteracts anticholinergics by activating nicotinic acetylcholine receptors . Caffeine (although an adenosine receptor antagonist ) can counteract the anticholinergic symptoms by reducing sedation and increasing acetylcholine ...
Frequently reported symptoms include feeling very tired, confusion, and headaches. [7] Seizures and symptoms similar to those of a stroke can also be seen. [ 7 ] Other symptoms include, but are not limited to jaundice or paleness of the skin, a fast heart rate or shortness of breath , [ 8 ] or dots on the skin known as petechiae . [ 9 ]