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The Bethesda system (TBS), officially called The Bethesda System for Reporting Cervical Cytology, is a system for reporting cervical or vaginal cytologic diagnoses, [1] used for reporting Pap smear results. It was introduced in 1988 [2] and revised in 1991, [3] 2001, [1] [4] [5] and 2014. [6]
Cytopathology suspicious for Hürthle cell neoplasm (Bethesda category IV, rather than normal or hyperplastic Hürthle cells), Pap stain. [6] Cytopathology cannot distinguish Hürthle cell adenoma from Hürthle cell carcinoma, which requires histopathologic sections to see transcapsular or vascular invasion.
The typical threshold for treatment is CIN 2+, although a more restrained approach may be taken for young persons and pregnant women. Treatment for higher-grade CIN involves removal or destruction of the abnormal cervical cells by cryocautery , electrocautery , laser cautery , loop electrical excision procedure (LEEP), or cervical conization ...
Cytopathology suspicious for Hürthle cell neoplasm (Bethesda category IV, rather than Hürthle cell hyperplasia), Pap stain. [3] While Hurthle cells can occur in healthy thyroid glands, [1] they are often associated with Hashimoto's thyroiditis [4] and Graves' disease. [2]
Bethesda system Category Description Risk of malignancy [19] Recommendation [19] I Non diagnostic/unsatisfactory – Repeating FNAC with ultrasound-guidance in more than 3 months II Benign (colloid and follicular cells) 0–3%: Clinical follow-up III
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February 4, 2025 at 2:12 PM. Since the 1990s, a race-based method for assessing kidney function placed many Black patients lower on the transplant waitlist. However, thousands of these patients ...
Histopathology of NIFTP, H&E stain. [1]Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is an indolent thyroid tumor that was previously classified as an encapsulated follicular variant of papillary thyroid carcinoma, [2] necessitating a new classification as it was recognized that encapsulated tumors without invasion have an indolent behavior, [2] and may ...